Potassium Hydroxide → HCID 57421236, compound

Participants

Reaction Steps

A solution of acetic acid 2-{3-chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(5-methyl-pyrazin-2-yl)-propyl]-phenoxy}-ethyl ester in ethanol was added to a solution of KOH in ethanol. The reaction mixture was stirred for 3 h at r.t., before it was taken up in ethyl acetate, washed with water and brine, and the solvent was evaporated. Flash chromatography provided the title compound. MS (m/e)=391.0 (MH+).

Provenance & Evidence