2-Bromoethyl methyl ether → HCID 57474051, compound

HRID 333817Notes

Reaction equation

HRID 333817 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH:9]([CH3:23])[C:10]([C:16]1[CH:21]=[CH:20][NH:19][C:18](=[O:22])[CH:17]=1)([OH:15])[C:11]([F:14])([F:13])[F:12].Br[CH2:25][CH2:26][O:27][CH3:28]>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH:9]([CH3:23])[C:10]([C:16]1[CH:21]=[CH:20][N:19]=[C:18]([O:22][CH2:25][CH2:26][O:27][CH3:28])[CH:17]=1)([OH:15])[C:11]([F:14])([F:13])[F:12]

Participants

3

Reactant 2

HCID 809722-Bromoethyl methyl etherHCID 57421256HCID 57421256, compound

Product 1

HCID 57474051HCID 57474051, compound

Procedure

The title compound was prepared in analogy to Example 120 from 4-[2-(2,4-Dichloro-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-1H-pyridin-2-one (Example 119, 100 mg) and 1-bromo-2-methoxy-ethane (0.031 mL). MS (m/e)=423.1 (MH+).

Sources & evidence

ORD record
ord-9fa0ccaaf22540b9876b33e48d3a2824
Source dataset
uspto-grants-2014_11
Patent number
US08883786B2

Reaction notes

Loading…