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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 334013Generated: October 26, 2026

3-Fluoro-4-methylbenzeneboronic acid → 1-(3-Fluoro-4-methyl-phenyl)-1H-[1,2,4]-triazole-3-carboxylic acid

https://huagongshe.com/reaction/334013

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-4-methylbenzeneboronic acidHCID 2782674—
Reactant1-(3-Chlorophenyl)-1H-1,2,4-triazole-3-carboxylic acidHCID 71301927—
ReactantHCID 178499122HCID 178499122—
Product1-(3-Fluoro-4-methyl-phenyl)-1H-[1,2,4]-triazole-3-carboxylic acidHCID 86688240—

Reaction Steps

This intermediate was prepared from 3-fluoro-4-methylphenylboronic acid and methyl 1,2,4-triazole-3-carboxylate in two steps according to the preparation of 1-(3-chloro-phenyl)-1H-[1,2,4]-triazole-3-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08883789B2
Source datasetuspto-grants-2014_11
ORD IDord-83edebd079c2490eb9b7fe792c23ccf2
Source noteuspto-grants-2014_11