HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86688251, compound → (3,3-Dimethyl-1-piperazinyl)(6-methoxy-2-pyridinyl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86688251 | HCID 86688251 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (3,3-Dimethyl-1-piperazinyl)(6-methoxy-2-pyridinyl)methanone | HCID 86688252 | — |
Reaction Steps
A mixture of 1.10 g (2.87 mmol) 4-(6-methoxy-pyridine-2-carbonyl)-2,2-dimethyl-piperazine-1-carboxylic acid benzyl ester and 100 mg palladium on carbon in 20 mL methanol was hydrogenated at RT for 12 h at 3 bar. The catalyst was removed by filtration and the solvent was evaporated in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08883789B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-a19f4a0946e746b6bbd57e8f9b6473e4 |
| Source note | uspto-grants-2014_11 |