HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Boc-3,3-dimethylpiperazine → (2,2-Dimethyl-piperazin-1-yl)-[2-(3-fluoro-phenyl)-2H-tetrazol-5-yl]-methanone trifluoroacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Boc-3,3-dimethylpiperazine | HCID 22710387 | — |
| Reactant | 2-(3-Fluoro-phenyl)-2H-tetrazole-5-carboxylic acid | HCID 82283623 | — |
| Reactant | (2,2-dimethyl-piperazin-1-yl)-(1-phenyl-1-H-[1,2,4]triazol-3-yl)-methanone trifluoroacetate | HCID 86688259 | — |
| Product | (2,2-Dimethyl-piperazin-1-yl)-[2-(3-fluoro-phenyl)-2H-tetrazol-5-yl]-methanone trifluoroacetate | HCID 86688271 | — |
Reaction Steps
This intermediate was prepared from 2-(3-fluoro-phenyl)-2H-tetrazole-5-carboxylic acid and 3,3-dimethyl-piperazine-1-carboxylic acid tert-butyl ester in two steps according to the preparation of (2,2-dimethyl-piperazin-1-yl)-(1-phenyl-1-H-[1,2,4]-triazol-3-yl)-methanone trifluoroacetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08883789B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-d4b2b1c2b674483c8b66726bc1033d2f |
| Source note | uspto-grants-2014_11 |