HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 84696473, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-Isoquinolinecarboxylic acid, 1,6-dimethoxy-, methyl ester | HCID 86688283 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 84696473 | HCID 84696473 | — |
Reaction Steps
500 mg (2.02 mmol) 1,6-dimethoxy-isoquinoline-3-carboxylic acid methyl ester was dissolved in 20 mL MeOH and treated with 2.50 mL 4 M aqueous NaOH solution at RT for 12 h. The solvent was removed by distillation, the residue taken up in water and acidified with 4 M aqueous hydrochlorid acid. The precipitate was filtered off, washed with water and purified by HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08883789B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-9c1a3869d16e4b3b965d2666b7d5a2aa |
| Source note | uspto-grants-2014_11 |