HCID 86688292, compound → HCID 86688309, compound

Participants

Reaction Steps

A mixture of 17 mg (34 μmol) [1-(3-chloro-phenyl)-1H-[1,2,4]-triazol-3-yl]-{4-[6-(3,6-dihydro-2H-pyran-4-yl)-pyridine-2-carbonyl]-2,2-dimethyl-piperazin-1-yl}-methanone and 4 mg palladium on carbon in 5.0 mL EtOAc was hydrogenated at RT for 4 days. The catalyst was removed by filtration and the solvent was evaporated in vacuo. The resulting residue was purified by HPLC.

Provenance & Evidence