HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 334089Generated: October 29, 2026
Cyclopentylacetic acid → [4-(2-cyclopentylmethyl-3-methyl-3H-benzoimidazole-5-carbonyl)-2,2-dimethyl-piperazin-1-yl]-(1-phenyl-1H-[1,2,4]-triazol-3-yl)-methanone
https://huagongshe.com/reaction/334089
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Cyclopentylacetic acid | HCID 71606 | — |
| Reactant | [4-(4-Amino-3-methylamino-benzoyl)-2,2-dimethyl-piperazin-1-yl]-(1-phenyl-1H-[1,2,4]-triazol-3-yl)-methanone | HCID 86688295 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | [4-(2-cyclopentylmethyl-3-methyl-3H-benzoimidazole-5-carbonyl)-2,2-dimethyl-piperazin-1-yl]-(1-phenyl-1H-[1,2,4]-triazol-3-yl)-methanone | HCID 71603308 | — |
Reaction Steps
A mixture of 123 mg (0.284 mmol) [4-(4-amino-3-methylamino-benzoyl)-2,2-dimethyl-piperazin-1-yl]-(1-phenyl-1H-[1,2,4]-triazol-3-yl)-methanone and 500 μL (3.99 mmol) cyclopentylacetic acid was stirred at 200° C. for 30 min. The reaction mixture was diluted with DMF and purified by HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08883789B2 |
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| Source dataset | uspto-grants-2014_11 |
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| ORD ID | ord-bdb7e99dc639425babab58092907e107 |
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| Source note | uspto-grants-2014_11 |
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