反应详情

2-(2H-Benzotriazol-2-yl)-4-methyl-phenol (2.3 g, 10 mmol) is dissolved in acetic acid (30 mL) at 80° C. Zinc chloride (140 mg, 1 mmol) and paraformaldehyde (390 mg, 13 mmol) are added and HCl gas is passed through the reaction mixture for 12 hours at 80° C. The product, which precipitates after cooling to room temperature, is filtered off, washed with small amounts of cold ethyl acetate and dried at 60° C. under vacuum to yield 1.9 g of 2-(2H-benzotriazol-2-yl)-6-chloromethyl-4-methyl-phenol.

1. customThe product, which precipitates
2. filtrationis filtered off
3. washwashed with small amounts of cold ethyl acetate
4. customdried at 60° C. under vacuum