Sodium Bicarbonate → HCID 66769631, compound

HRID 335066Notes

Reaction equation

HRID 335066 reaction equation
[CH3:1][C:2]1[CH:26]=[C:25]([CH3:27])[CH:24]=[C:23]([CH3:28])[C:3]=1[C:4]([P:6]([CH2:19][C:20]([OH:22])=[O:21])([C:8](=[O:18])[C:9]1[C:14]([CH3:15])=[CH:13][C:12]([CH3:16])=[CH:11][C:10]=1[CH3:17])=[O:7])=[O:5].C(=O)([O-])O.[Na+:33]>O>[CH3:15][C:14]1[CH:13]=[C:12]([CH3:16])[CH:11]=[C:10]([CH3:17])[C:9]=1[C:8]([P:6]([C:4](=[O:5])[C:3]1[C:23]([CH3:28])=[CH:24][C:25]([CH3:27])=[CH:26][C:2]=1[CH3:1])([CH2:19][C:20]([O-:22])=[O:21])=[O:7])=[O:18].[Na+:33]

Participants

4

Reactant 2

HCID 516892Sodium BicarbonateHCID 66769632HCID 66769632, compound2×

Product 1

HCID 66769631HCID 66769631, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2-(bis(2,4,6-trimethylbenzoyl)phosphoryl)acetic acid (example 18b) (0.1 g, 0.25 mmol, 1 eq.) is suspended in distilled water (2 ml) and sodium hydrogencarbonate (21.0 mg, 0.25 mmol, 1 eq.) is added. A clear pale yellow solution is obtained. After removing the water in vacuo at room temperature, a pale yellow crystalline powder is isolated (Yield: quantitative). It is evident that the same procedure can be performed to synthesise other alkali salts of 2-(bis(2,4,6-trimethylbenzoyl)phosphoryl)acetic acid from carbonates or hydrogen-carbonates (e.g. with potassium hydrogen carbonate, or lithium carbonate).

Workup

  1. customA clear pale yellow solution is obtained
  2. customAfter removing the water in vacuo at room temperature
  3. customa pale yellow crystalline powder is isolated (Yield: quantitative)

Sources & evidence

ORD record
ord-466e4ac0158241059ad48ec43f19d6b5
Source dataset
uspto-grants-2014_11
Patent number
US08883872B2

Reaction notes

Loading…