2-Bromopyridine → pyridin-2-yl(tetrahydro-2H-thiopyran-4-yl)methanol

HRID 335158Notes

Reaction equation

HRID 335158 reaction equation

Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1.[S:8]1[CH2:13][CH2:12][CH:11]([CH:14]=[O:15])[CH2:10][CH2:9]1>>[N:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[CH:14]([CH:11]1[CH2:12][CH2:13][S:8][CH2:9][CH2:10]1)[OH:15]

Participants

3

Reactant 2

HCID 79732-Bromopyridine

HCID 20143720Thiane-4-carbaldehyde

Product 1

HCID 66995230pyridin-2-yl(tetrahydro-2H-thiopyran-4-yl)methanol

Procedure

Prepared according to the method of Example 225, Step A, from 2-bromopyridine and tetrahydro-2H-thiopyran-4-carbaldehyde.

Workup

customPrepared

Sources & evidence

ORD record: ord-ee1495667eb0405196ab493b829307a6
Source dataset: uspto-grants-2014_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08883828B2

Reaction notes

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