反应详情

To a solution of 1-(naphth-1-yl)-1-propanone (4.0 g) in anhydrous tetrahydrofuran (50 ml) was added phenyltrimethylammonium tribromide (8.0 g). The resulting mixture was stirred overnight at room temperature then partitioned between petroleum ether and aqueous sodium carbonate solution. The organic layer was separated, washed with water, brine, dried with sodium sulphate, filtered and evaporated in vacuo to yield crude 2-bromo-1-(naphth-1-yl)-1-propanone (5.7 g).

1. customthen partitioned between petroleum ether and aqueous sodium carbonate solution
2. customThe organic layer was separated
3. washwashed with water, brine
4. dry with materialdried with sodium sulphate
5. filtrationfiltered
6. customevaporated in vacuo