HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 336086Generated: October 30, 2026
Hydrochloric Acid → 4-[1-Furan-3-yl-meth-(e)-ylidene]-2-(2,4,6-trimethyl-phenyl)-cyclopentane-1,3-dione
https://huagongshe.com/reaction/336086
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 5-(Furan-3-yl-hydroxy-methyl)-3-methoxy-2-(2,4,6-trimethyl-phenyl)-cyclopent-2-enone | HCID 66683881 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 4-[1-Furan-3-yl-meth-(e)-ylidene]-2-(2,4,6-trimethyl-phenyl)-cyclopentane-1,3-dione | HCID 66683882 | — |
Reaction Steps
To a solution of 5-(furan-3-yl-hydroxy-methyl)-3-methoxy-2-(2,4,6-trimethyl-phenyl)-cyclopent-2-enone (770 mg) in acetone (2 ml) is added 2N hydrochloric acid (2 ml) and the resulting suspension heated to 120° C. for 30 minutes. The crude reaction mixture is concentrated in vacuuo and purified by flash chromatography to give 4-[1-furan-3-yl-meth-(E)-ylidene]-2-(2,4,6-trimethyl-phenyl)-cyclopentane-1,3-dione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08889595B2 |
|---|
| Source dataset | uspto-grants-2014_11 |
|---|
| ORD ID | ord-9d20b3f221bf4044bb2301bea69520e5 |
|---|
| Source note | uspto-grants-2014_11 |
|---|
