反应详情

温度

120 °C

To a solution of 5-(furan-3-yl-hydroxy-methyl)-3-methoxy-2-(2,4,6-trimethyl-phenyl)-cyclopent-2-enone (770 mg) in acetone (2 ml) is added 2N hydrochloric acid (2 ml) and the resulting suspension heated to 120° C. for 30 minutes. The crude reaction mixture is concentrated in vacuuo and purified by flash chromatography to give 4-[1-furan-3-yl-meth-(E)-ylidene]-2-(2,4,6-trimethyl-phenyl)-cyclopentane-1,3-dione.

1. customThe crude reaction mixture
2. concentrationis concentrated in vacuuo
3. custompurified by flash chromatography