HCID 58564023, compound → Tetrahydro-2H-thiopyran-4-carboxylic acid 1,1-dioxide

HRID 336203Notes

Reaction equation

HRID 336203 reaction equation
[O:1]=[S:2]1(=[O:14])[CH2:7][CH2:6][C:5](C(O)=O)([C:8]([OH:10])=[O:9])[CH2:4][CH2:3]1>CN(C=O)C>[O:1]=[S:2]1(=[O:14])[CH2:7][CH2:6][CH:5]([C:8]([OH:10])=[O:9])[CH2:4][CH2:3]1

Participants

3

Reactant 1

HCID 58564023HCID 58564023, compound

Product 1

HCID 1491755Tetrahydro-2H-thiopyran-4-carboxylic acid 1,1-dioxide

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

In a microwave vial is added 1,1-Dioxo-tetrahydro-1λ6-thiopyran-4,4-dicarboxylic acid (112 mg; 0.504 mmol), 2% cross-linked poly-4-vinylpyridine (225 mg) and DMF (2.1 mL). The vial is sealed and placed into microwave oven for 10 minutes at 95° C. After cooling, the mixture is filtered through filter paper and washed the paper with diethyl ether. The filtrate is concentrated in vacuo to afford the title compound.

Workup

  1. customThe vial is sealed
  2. temperatureAfter cooling
  3. filtrationthe mixture is filtered
  4. filtrationthrough filter paper
  5. washwashed the paper with diethyl ether
  6. concentrationThe filtrate is concentrated in vacuo

Sources & evidence

ORD record
ord-7eb3610a0c0e4937a651665e8d86db4a
Source dataset
uspto-grants-2014_11
Patent number
US08889670B2

Reaction notes

Loading…