HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 71667129, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Bromo-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone | HCID 63679846 | — |
| Reactant | 3,5-bis-(4-Fluoro-phenyl)-1H-(1,2,4)triazole | HCID 86686515 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 71667129 | HCID 71667129 | 69.1% |
Reaction Steps
100 mg 3,5-bis-(4-fluoro-phenyl)-1H-(1,2,4)triazole, 111 mg 2-bromo-1-(4-pyrimidin-2-yl-piperazin-1-yl)-ethanon and 237 mg potassiumcarbonat in 5 mL acetone was stirred 24 h at RT. The reaction was filtered and the filtrate was evaporated. The residue was crystallized with acetonitrile to yield 124 mg of the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08889677B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-e32d1c6fcde94e279d860502355a0586 |
| Source note | uspto-grants-2014_11 |