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HRID336495

反应详情

EQUATION

反应方程式

HRID 336495 的结构方程式

REACTANTS

反应物

2
结构：CCS(=O)(=O)Cl
HCID11667

Ethanesulfonyl chloride

C2H5ClO2S

结构：Clc1cc(NC2CCCC2)c2[nH]c(C3=N[C@H](CCN4CCNCC4)CS3)cc2c1
HCID59543099

未命名化合物

PRODUCTS

生成物

1
结构：CCS(=O)(=O)N1CCN(CC[C@@H]2CSC(c3cc4cc(Cl)cc(NC5CCCC5)c4[nH]3)=N2)CC1
HCID59543045

未命名化合物

PROCEDURE

实验过程

{5-Chloro-2-[(R)-4-(2-piperazin-1-yl-ethyl)-4,5-dihydro-thiazol-2-yl]-1H-indol-7-yl}-cyclopentyl-amine prepared in Example 160 and ethyl sulfonylchloride were reacted according to the same procedure as Step B of Preparation 29 to give the title compound.

WORKUP

后处理

  1. customaccording to the same procedure as Step B of Preparation 29