HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 2-azido-6-azaspiro[3.4]octane-6-carboxylate → tert-Butyl 2-amino-6-azaspiro[3.4]octane-6-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 2-azido-6-azaspiro[3.4]octane-6-carboxylate | HCID 86660640 | — |
| Catalyst | Lindlars catalyst | HCID 131709914 | — |
| Product | tert-Butyl 2-amino-6-azaspiro[3.4]octane-6-carboxylate | HCID 56962195 | 58.4% |
Reaction Steps
The process is performed according to the procedure described in Example 6 (step 6.4). Starting with 1.33 g (5.30 mmol) of tert-butyl 2-azido-6-azaspiro[3.4]octane-6-carboxylate (isomer 2′) and 0.54 g (2.65 mmol) of Lindlar catalyst (PdCaCO3), 0.70 g of product is obtained in the form of an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08889702B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-9b53e02da1154478abc6228db4266c52 |
| Source note | uspto-grants-2014_11 |