Pyrazole → HCID 86681270, compound

HRID 336610Notes

Reaction equation

HRID 336610 reaction equation
[C:1]12(CO)[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[NH:13]1[CH:17]=[CH:16][CH:15]=[N:14]1.[CH3:18]C1C(B2OC(C)(C)C(C)(C)O2)=C(C)NN=1>>[CH:1]12[CH2:2][CH:3]3[CH2:4][CH:5]([CH2:6][CH:7]([CH2:9]3)[CH:8]1[CH2:18][N:13]1[CH:17]=[CH:16][CH:15]=[N:14]1)[CH2:10]2

Participants

4

Reactant 3

HCID 1048PyrazoleHCID 64556Tricyclo(3.3.1.1'3,7)dec-1-ylmethanolHCID 162177133,5-Dimethylpyrazole-4-boronic acid, pinacol ester

Product 1

HCID 86681270HCID 86681270, compound

Procedure

The title compound was prepared by substituting EXAMPLE 10A for 1-adamantanemethanol and pyrazole for 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole in EXAMPLE 2A.

Sources & evidence

ORD record
ord-0a8acff88b074f5194268bf5ac88ed65
Source dataset
uspto-grants-2014_11
Patent number
US08889675B2

Reaction notes

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