HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 336619Generated: October 30, 2026
HCID 86603565, compound → Imidazo[1,2-a]pyrazin-2-amine
https://huagongshe.com/reaction/336619
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 86603565 | HCID 86603565 | — |
| Solvent | Ammonia | HCID 222 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Imidazo[1,2-a]pyrazin-2-amine | HCID 69382803 | — |
Reaction Steps
2,2,2-Trifluoro-N-(imidazo[1,2-a]pyrazin-2-yl)acetamide (prepared as described in WO2004/058266A1, 520 mg) was dissolved in 7N NH3 in methanol (4.0 mL), and heated at 68° C. in a sealed tube for 6 hours. The reaction mixture was then cooled and concentrated to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08889675B2 |
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| Source dataset | uspto-grants-2014_11 |
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| ORD ID | ord-b6c8f7493a284037beef35c78fe7cee8 |
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| Source note | uspto-grants-2014_11 |
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