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HRID336673

反应详情

EQUATION

反应方程式

HRID 336673 的结构方程式

REACTANTS

反应物

3
反应SMILES：O=Cc1cccnc1
HCID10371

3-Pyridinecarboxaldehyde

C6H5NO

反应SMILES：COc1cc(N)c(C(N)=O)c(OC)c1
HCID20349016

2-Amino-4,6-dimethoxybenzamide

C9H12N2O3

反应SMILES：COc1cc(OC)c2c(=O)[nH]c(-c3ccccn3)nc2c1
HCID136037998

未命名化合物

PRODUCTS

产物

1
反应SMILES：COc1cc(OC)c2c(=O)[nH]c(-c3cccnc3)nc2c1
HCID135907864

未命名化合物

收率 48%

PROCEDURE

实验过程

5,7-Dimethoxy-2-(pyridin-3-yl)quinazolin-4(3H)-one was synthesized from 2-amino-4,6-dimethoxybenzamide and 3-pyridine carboxaldehyde, using the method described for 5,7-dimethoxy-2-(pyridin-2-yl)quinazolin-4(3H)-one. 5,7-Dimethoxy-2-(pyridin-3-yl)quinazolin-4(3H)-one (105 mg, 48%) was isolated as a white solid. Selected data: MS (m/z): 284.0; MP 257-259° C. (hydrochloride).