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HRID336696

反应详情

EQUATION

反应方程式

HRID 336696 的结构方程式

REACTANTS

反应物

3
结构：COc1cc(N)c(C(N)=O)cc1OC
HCID10867236

2-amino-4,5-dimethoxybenzamide

C9H12N2O3

结构：O=Cc1ccc(N(CCO)CCO)cc1
HCID12824965

4-[Bis(2-hydroxyethyl)amino]benzaldehyde

C11H15NO3

结构：COc1cc(OC)c2c(=O)[nH]c(-c3ccccn3)nc2c1
HCID136037998

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc2nc(-c3ccc(N(CCO)CCO)cc3)[nH]c(=O)c2cc1OC
HCID136037964

未命名化合物

收率 24%

PROCEDURE

实验过程

2-(4-(Bis(2-hydroxyethyl)amino)phenyl)-6,7-dimethoxyquinazolin-4(3H)-one was synthesized from 2-amino-4,5-dimethoxy-benzamide and 4-(N,N-bis(2-hydroxyethyl)amino)benzaldehyde, using the method described for 5,7-dimethoxy-2-(pyridin-2-yl)quinazolin-4(3H)-one. 2-(4-(Bis(2-hydroxyethyl)amino)phenyl)-6,7-dimethoxyquinazolin-4(3H)-one (72 mg, 24%) was isolated as a yellow solid. Selected data: MS (m/z): 386.15; MP 268-270° C.