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HRID337067

反应详情

EQUATION

反应方程式

HRID 337067 的结构方程式

REACTANTS

反应物

2
反应SMILES：CN
HCID6329

Methylamine

CH5N

反应SMILES：Cc1c(F)cc(C(=O)NC2CC2)cc1-n1ccnc(NC(C)(C)c2ccccc2OCCCl)c1=O
HCID66689625

未命名化合物

PRODUCTS

产物

1
反应SMILES：CNCCOc1ccccc1C(C)(C)Nc1nccn(-c2cc(C(=O)NC3CC3)cc(F)c2C)c1=O
HCID66689384

未命名化合物

PROCEDURE

实验过程

The title product was prepared from 3-[3-[[1-[2-(2-chloroethoxy)phenyl]-1-methylethyl]amino]-2-oxo-1(2H)-pyrazinyl]-N-cyclopropyl-5-fluoro-4-methyl-benzamide (Example 169h) and methylamine using a similar method to that described for example 167f. Purification was by RPHPLC (0.2% ammonia/MeCN gradient on a Phenominex column).

WORKUP

后处理

  1. customPurification