HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 71060145, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 71059991 | HCID 71059991 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 71060145 | HCID 71060145 | 113.8% |
Reaction Steps
{1-[3-Chloro-4-(3-phenyl-propionylamino)-benzenesulfonyl]-piperidin-4-yl}-carbamic acid tert-butyl ester (0.09 g, 0.1 mmol) was suspended in a 4M solution of HCl in Dioxane (5 ml). The resulting suspension was stirred at room temperature for 3 hours. After this time the solution was concentrated under vacuum to give the title compound (0.048 g, 99% yield) as a colourless oil which was taken on directly without further purification. Tr=1.71 min, m/z (ES+) (M+H)+ 422.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08889716B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-34df1506ad7247e9b9f242a04356d84e |
| Source note | uspto-grants-2014_11 |