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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 337224Generated: October 30, 2026

Hydrochloric Acid → HCID 71060145, compound

https://huagongshe.com/reaction/337224

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 71059991HCID 71059991—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 71060145HCID 71060145113.8%

Reaction Steps

{1-[3-Chloro-4-(3-phenyl-propionylamino)-benzenesulfonyl]-piperidin-4-yl}-carbamic acid tert-butyl ester (0.09 g, 0.1 mmol) was suspended in a 4M solution of HCl in Dioxane (5 ml). The resulting suspension was stirred at room temperature for 3 hours. After this time the solution was concentrated under vacuum to give the title compound (0.048 g, 99% yield) as a colourless oil which was taken on directly without further purification. Tr=1.71 min, m/z (ES+) (M+H)+ 422.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08889716B2
Source datasetuspto-grants-2014_11
ORD IDord-34df1506ad7247e9b9f242a04356d84e
Source noteuspto-grants-2014_11