2-Nitroresorcinol → 2-Aminoresorcinol

HRID 337341Notes

Reaction equation

HRID 337341 reaction equation
[N+:1]([C:4]1[C:10]([OH:11])=[CH:9][CH:8]=[CH:7][C:5]=1[OH:6])([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[C:10]([OH:11])=[CH:9][CH:8]=[CH:7][C:5]=1[OH:6]

Participants

4

Reactant 1

HCID 117602-Nitroresorcinol

Product 1

HCID 694512-AminoresorcinolYield 90.2%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

465 mg of 2-nitroresorcinol was dissolved in 9.3 ml of ethanol, and 230 mg of 10% palladium/carbon was added, and stirred under hydrogen atmosphere at room temperature for 1 hour. After the insoluble matter was filtered off, solvent was distilled off under reduced pressure to yield 338.5 mg of the title compound.

Workup

  1. filtrationAfter the insoluble matter was filtered off
  2. distillationsolvent was distilled off under reduced pressure

Sources & evidence

ORD record
ord-1261bf0bc10d482cb5c583bee02b0bae
Source dataset
uspto-grants-2014_11
Patent number
US08889727B2

Reaction notes

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