HCID 86703257, compound → HCID 86703258, compound

HRID 337351Notes

Reaction equation

HRID 337351 reaction equation
[CH3:1][S:2]([O:5][C:6]1[CH:11]=[C:10]([CH2:12][CH3:13])[C:9](Cl)=[CH:8][C:7]=1[N+:15]([O-])=O)(=[O:4])=[O:3]>C(O)C.[Pd]>[CH3:1][S:2]([O:5][C:6]1[CH:11]=[C:10]([CH2:12][CH3:13])[CH:9]=[CH:8][C:7]=1[NH2:15])(=[O:4])=[O:3]

Participants

4

Reactant 1

HCID 86703257HCID 86703257, compound

Product 1

HCID 86703258HCID 86703258, compoundYield 48.7%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

200 mg of 4-chloro-5-ethyl-2-nitrophenyl methanesulfonate was dissolved in 4 ml of ethanol, and 200 mg of 10% palladium/carbon was added and stirred under hydrogen atmosphere at room temperature for 4 hours. After the insoluble matter was filtered off, the solvent was distilled off under reduced pressure to yield 74.9 mg of the title compound.

Workup

  1. filtrationAfter the insoluble matter was filtered off
  2. distillationthe solvent was distilled off under reduced pressure

Sources & evidence

ORD record
ord-d75ffef8555a48e083557ed81ab0eccc
Source dataset
uspto-grants-2014_11
Patent number
US08889727B2

Reaction notes

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