反应详情

To a solution of 3-hydroxy-4-nitrophenyl acetate (3.0 g) in ethyl acetate (50 mL), 300 mg of palladium/carbon (10%) was added under nitrogen atmosphere. The resulting mixture was stirred under hydrogen atmosphere for 10 h at room temperature. The insoluble material was filtered off and the filtrate was concentrated under reduced pressure. The residue was purified by the column chromatography over silica gel using hexane/ethyl acetate(1:1) to give the title compound (2.48 g).

1. filtrationThe insoluble material was filtered off
2. concentrationthe filtrate was concentrated under reduced pressure
3. customThe residue was purified by the column chromatography over silica gel