HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2,3-dihydro-1H-inden-5-yl)boronic acid → 5-(2,3-dihydro-1H-inden-5-yl)-4-methoxythiophene-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2,3-dihydro-1H-inden-5-yl)boronic acid | HCID 22240187 | — |
| Reactant | 4-Methoxy-5-(5,6,7,8-tetrahydronaphthalen-2-yl)thiophene-3-carbonitrile | HCID 68161411 | — |
| Product | 5-(2,3-dihydro-1H-inden-5-yl)-4-methoxythiophene-3-carbonitrile | HCID 68160636 | 85.6% |
Reaction Steps
Synthesis was carried out in the same manner as in Synthesis Method 2 (4) in Reference Synthetic Example 3 by using 4.08 g (0.0252 mol) of (2,3-dihydro-1H-inden-5-yl)boronic acid described in Reference Synthetic Example 5(1) to obtain 5.0 g of the desired product (yield: 85.6%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08889732B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-40fbbe33aaef4172b2bf3f84150e2ebd |
| Source note | uspto-grants-2014_11 |