HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[4-Hydroxy-5-(5,6,7,8-tetrahydronaphthalen-2-yl)thiophen-3-yl]ethanone → 1-[5-(2,3-dihydro-1H-inden-5-yl)-4-hydroxythiophen-3-yl]ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[4-Hydroxy-5-(5,6,7,8-tetrahydronaphthalen-2-yl)thiophen-3-yl]ethanone | HCID 68161642 | — |
| Reactant | 1-[5-(2,3-dihydro-1H-inden-5-yl)-4-methoxythiophen-3-yl]ethanone | HCID 68162013 | — |
| Product | 1-[5-(2,3-dihydro-1H-inden-5-yl)-4-hydroxythiophen-3-yl]ethanone | HCID 68161209 | 37.3% |
Reaction Steps
Synthesis was carried out in the same manner as in Synthesis Method 2 (6) in Reference Synthetic Example 3 by using 3.5 g (0.0129 mol) of 1-[5-(2,3-dihydro-1H-inden-5-yl)-4-methoxythiophen-3-yl]ethanone to obtain 1.24 g of the desired product (yield: 37.3%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08889732B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-4a09f03689a3430f9797742a565dbaf2 |
| Source note | uspto-grants-2014_11 |