反应详情

温度

180 °C

The mixture of triphenylphosphine (3.47 g, 13.24 mmol) and 1,1′-(2-nitro-[1,1′-biphenyl]-4,4′-diyl)diethanone (1.5 g, 5.30 mmol) in 1,2-dichlorobenzene (o-DCB) (15.90 mL) was heated at 180° C. under microwave irradiation for 1 h. The reaction mixture was cooled and poured in to the hexane (50 mL). Most of the impurities were removed by precipitation from hexane. The compound was further purified on silica gel ((0-100% EtOAc/Hexane). Fractions were concentrated to give the title compound as a yellow solid.

1. temperatureThe reaction mixture was cooled
2. customMost of the impurities were removed by precipitation from hexane
3. customThe compound was further purified on silica gel ((0-100% EtOAc/Hexane)
4. concentrationFractions were concentrated