反应详情

温度

60 °C

Sodium ethoxide (62.0 mg, 0.900 mmol) was dissolved in ethanol (2 mL), and Compound 531 (120 mg, 0.300 mmol) was added thereto, followed by stirring at 60° C. for 3 hours. The reaction mixture was concentrated under reduced pressure, and the resulting residue was purified through silica gel column chromatography (chloroform:methanol=99:1) and crystallized from 2-propanol to afford the entitled Compound 532 (53.4 mg, 49%).

1. concentrationThe reaction mixture was concentrated under reduced pressure
2. customthe resulting residue was purified through silica gel column chromatography (chloroform:methanol=99:1)
3. customcrystallized from 2-propanol