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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 337968Generated: October 30, 2026

p-Toluenesulfonic acid → HCID 89962122, compound

https://huagongshe.com/reaction/337968

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Toluenesulfonic acidHCID 6101—
ReactantHCID 89962338HCID 89962338—
SolventTolueneHCID 1140—
ProductHCID 89962122HCID 8996212297.4%

Reaction Steps

The reaction and aftertreatment were conducted in the same manner as in Example 99b by using the 4,4-difluoro-1-[1-(methoxymethyl)-1H-pyrazol-4-yl]cyclohexanol (0.20 g, 0.81 mmol) prepared in Example 147a, p-toluenesulfonic acid (14 mg, 0.081 mmol) and toluene (5.0 mL), to yield the title compound (0.18 g, 97%) as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08889741B2
Source datasetuspto-grants-2014_11
ORD IDord-0ec6d00480604800bef0d9f2ea074c10
Source noteuspto-grants-2014_11