Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 337999Generated: October 31, 2026

Hydrochloric Acid → HCID 89963607, compound

https://huagongshe.com/reaction/337999

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 89962418HCID 89962418—
SolventMethanolHCID 887—
ProductHCID 89963607HCID 8996360787%

Reaction Steps

The reaction and aftertreatment were conducted in the same manner as in Example 158e by using the 5-chloro-2-fluoro-4-{[(1R,2S)-2-{1-[(2-methoxyethoxy)methyl]-1H-pyrazol-5-yl}cyclohexyl]oxy}-N-(pyrimidin-4-yl)benzenesulfonamide (139 mg, 0.257 mmol) prepared in Example 159c, 6 M HCl (5.0 mL) and methanol (4.0 mL), to yield the title compound (101 mg, 73%) as a pale yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08889741B2
Source datasetuspto-grants-2014_11
ORD IDord-06c86ed5aad84d8bbe94768089307bf4
Source noteuspto-grants-2014_11