反应详情

温度

150 °C

2-(2-Bromo-phenylsulfanyl)-5-nitro-benzoic acid (34 g, 96 mmol) was suspended in methanesulphonic acid (400 ml) and heated at 150° C. The crude mixture was slowly poured onto ice with vigorous stirring and the precipitate formed was filtered. The solid was suspended into water (50 ml) quenched to pH 7-8 with conc. ammonia solution and filtered. The yellow/lime colored solid was dried under vacuum at 50° C. to give the crude title compound, which was used without any further purification (23.09 g, 72%).

1. customthe precipitate formed
2. filtrationwas filtered
3. customquenched to pH 7-8 with conc. ammonia solution
4. filtrationfiltered
5. dry with materialThe yellow/lime colored solid was dried under vacuum at 50° C.