HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Isopropylaniline → N-(3-isopropylphenyl)-6-(2-(methylthio)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl)picolinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Isopropylaniline | HCID 458679 | — |
| Reactant | 6-[2-(Methylthio)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-6-yl]pyridine-2-carboxylic acid | HCID 86695835 | — |
| Product | N-(3-isopropylphenyl)-6-(2-(methylthio)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl)picolinamide | HCID 86695837 | — |
Reaction Steps
In a manner similar to that described in Example 108, a mixture of 6-[2-(methylthio)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-6-yl]pyridine-2-carboxylic acid and 3-isopropylaniline were converted to the title compound (560 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08889870B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-25716feea5964748b21a1269e318b7a2 |
| Source note | uspto-grants-2014_11 |