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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 338719Generated: October 30, 2026

2-(Methylthio)-5,6,7,8-tetrahydropyrido[4,3-D]pyrimidine → 2-[2-(methylthio)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]-N-phenylisonicotinamide

https://huagongshe.com/reaction/338719

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Methylthio)-5,6,7,8-tetrahydropyrido[4,3-D]pyrimidineHCID 55263670—
Reactant2-Bromo-N-phenyl-isonicotinamideHCID 86695840—
Product2-[2-(methylthio)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]-N-phenylisonicotinamideHCID 86695845—

Reaction Steps

In a manner similar to that described for Example 138, 2-(methylsulfanyl)-5,6,7,8-tetrahydropyrido[4,3-d]-pyrimidine and 2-bromo-N-phenyl-isonicotinamide were converted to the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08889870B2
Source datasetuspto-grants-2014_11
ORD IDord-3522751c16ba4f2bba13953332442d9f
Source noteuspto-grants-2014_11