HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → 7-Methoxy-6-methylquinoline-2-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Selenium Dioxide | HCID 24007 | — |
| Reactant | Sulfuric acid magnesium salt (1:1) | HCID 24083 | — |
| Reactant | 7-Methoxy-2,6-dimethylquinoline | HCID 86707471 | — |
| Solvent | 1,4-Dioxane--water (1/1) | HCID 21886435 | — |
| Product | 7-Methoxy-6-methylquinoline-2-carbaldehyde | HCID 86707472 | — |
Reaction Steps
To 7-methoxy-2,6-dimethylquinoline (580 mg, 3.10 mmol) in dioxane/water (15/0.015 mL) was added selenium dioxide (447 mg, 4.03 mmol) and the reaction was heated to reflux for 5 hours. After cooling, DCM was added followed by MgSO4. After concentration, the residue was used in the next step without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08889704B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-c7f90c8963af42e3a605b51aad392744 |
| Source note | uspto-grants-2014_11 |