反应详情

To 7-methoxy-2,6-dimethylquinoline (580 mg, 3.10 mmol) in dioxane/water (15/0.015 mL) was added selenium dioxide (447 mg, 4.03 mmol) and the reaction was heated to reflux for 5 hours. After cooling, DCM was added followed by MgSO4. After concentration, the residue was used in the next step without purification.

1. temperaturethe reaction was heated
2. temperatureto reflux for 5 hours
3. temperatureAfter cooling
4. concentrationAfter concentration
5. customthe residue was used in the next step without purification