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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 33920Generated: October 29, 2026

Ammonium formate → HCID 135988008, compound

https://huagongshe.com/reaction/33920

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmonium formateHCID 2723923—
ReactantHCID 59797508HCID 59797508—
CatalystPalladium hydroxideHCID 9942167—
SolventMethanolHCID 887—
ProductHCID 135988008HCID 13598800886%

Reaction Steps

4-(4-(4-(Benzyloxy)phenyl)-2-methyloxazol-5-yl)pyridine was hydrogenated in the presence of ammonium formate and Pd(OH)2 in methanol for 1 h at 50° C. The catalyst was removed via filtration and the filtrate was concentrated. The resultant residue was dissolved in methylene chloride and dried with Na2SO4. Evaporation of the solvent gave 69 mg (86%) of the title compound as a brown solid. MS m/z: 253.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07429665B2
Source datasetuspto-grants-2008_09
ORD IDord-cb5c8609f66a41fd8bc2f7dc5c13570b
Source noteuspto-grants-2008_09