HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium formate → HCID 135988008, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium formate | HCID 2723923 | — |
| Reactant | HCID 59797508 | HCID 59797508 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 135988008 | HCID 135988008 | 86% |
Reaction Steps
4-(4-(4-(Benzyloxy)phenyl)-2-methyloxazol-5-yl)pyridine was hydrogenated in the presence of ammonium formate and Pd(OH)2 in methanol for 1 h at 50° C. The catalyst was removed via filtration and the filtrate was concentrated. The resultant residue was dissolved in methylene chloride and dried with Na2SO4. Evaporation of the solvent gave 69 mg (86%) of the title compound as a brown solid. MS m/z: 253.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07429665B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-cb5c8609f66a41fd8bc2f7dc5c13570b |
| Source note | uspto-grants-2008_09 |