Stannous chloride dihydrate → HCID 58341991, compound

HRID 339543Notes

Reaction equation

HRID 339543 reaction equation
[N+:1]([C:4]1[CH:28]=[CH:27][CH:26]=[CH:25][C:5]=1[C:6]([NH:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[S:16][C:17]3[CH:23]=[C:22]([CH3:24])[CH:21]=[CH:20][C:18]=3[N:19]=2)=[CH:11][CH:10]=1)=[O:7])([O-])=O.O.O.[Sn](Cl)Cl>CCO>[NH2:1][C:4]1[CH:28]=[CH:27][CH:26]=[CH:25][C:5]=1[C:6]([NH:8][C:9]1[CH:10]=[CH:11][C:12]([C:15]2[S:16][C:17]3[CH:23]=[C:22]([CH3:24])[CH:21]=[CH:20][C:18]=3[N:19]=2)=[CH:13][CH:14]=1)=[O:7]

Participants

4

Reactant 2

HCID 61436Stannous chloride dihydrateHCID 3120643HCID 3120643, compound

Product 1

HCID 58341991HCID 58341991, compoundYield 14%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared as described in the Nitro Reduction section using 2-nitro-N-[4-(6-methylbenzothiazol-2-yl)-phenyl]-benzamide (0.5 g, 1.28 mmol) and tin (II) chloride dihydrate (1.45 g, 6.42 mmol) in EtOH (50 ml) to give the title compound (0.063 g, 14%) as a tan needles after recrystallisation from EtOH.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-bae5e2cdb32e409ab4f49d1110a2af3f
Source dataset
uspto-grants-2014_11
Patent number
US08895313B2

Reaction notes

Loading…