HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous chloride dihydrate → HCID 28325553, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous chloride dihydrate | HCID 61436 | — |
| Reactant | Imidazo[2,1-b]thiazole, 2-methyl-6-(4-nitrophenyl)- | HCID 868202 | — |
| Reactant | Dichloromethane ethylacetate | HCID 21226138 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 28325553 | HCID 28325553 | 75% |
Reaction Steps
Prepared as described in the Nitro Reduction section using 2-methyl-6-(4-nitrophenyl) imidazo[2,1-b][1,3]thiazole (0.10 g, 0.386 mmol) and tin (II) chloride dihydrate (0.69 g, 3.09 mmol) in EtOH (15 ml) to give a pale orange solid (66 mg, 75%) after work-up and flash chromatography (1:1 DCM/EtOAc).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08895313B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-c78b93deb5d6428bb7fe4009722a037e |
| Source note | uspto-grants-2014_11 |