1-Azido-3-phenylpropan-2-ol → 1-Amino-3-phenylpropan-2-ol

Beteiligte Stoffe

Reaktionsschritte

To a stirring solution of 1-azido-3-phenyl-propan-2-ol (590 mg, 3.4 mmol) in 20 mL methanol under a nitrogen atmosphere was added 10 mg of Pd(OH)2/C (10%). Hydrogen gas was delivered via balloon. The solution was stirred overnight at room temperature. The catalyst was removed by filtering the solution through a bed of celite, and the filtrate was concentrated to give a clear oil under reduced pressure. M+1=152.

Herkunft & Nachweise