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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 33984Generated: October 29, 2026

(2-Amino-4,5-dimethoxy-phenyl)-[2-(acetoxymethyl)-pyrrolidin-1-yl]-methanone → (2-Hydroxymethyl-pyrrolidin-1-yl)-(2-isocyanato-4,5-dimethoxy-phenyl)-methanone

https://huagongshe.com/reaction/33984

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Amino-4,5-dimethoxy-phenyl)-[2-(acetoxymethyl)-pyrrolidin-1-yl]-methanoneHCID 69032329—
Reactant[2-(tert-Butyl-dimethyl-silanyloxymethyl)-pyrrolidin-1-yl]-(2-isocyanato-4,5-dimethoxy-phenyl)-methanoneHCID 131727078—
Product(2-Hydroxymethyl-pyrrolidin-1-yl)-(2-isocyanato-4,5-dimethoxy-phenyl)-methanoneHCID 86609298—

Reaction Steps

This was prepared from (6) in the same manner as above for (7).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07429658B2
Source datasetuspto-grants-2008_09
ORD IDord-2283df3c1040444e9223aa500008ea35
Source noteuspto-grants-2008_09