HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonate → HCID 178419901, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonate | HCID 85257 | — |
| Reactant | Trifluoromethanesulfonate | HCID 2758875 | — |
| Reactant | 6-Bromo-4-chloro-3-nitroquinoline | HCID 21984128 | — |
| Reactant | 4-Chloro-6-iodo-3-nitroquinoline | HCID 67470126 | — |
| Product | HCID 178419901 | HCID 178419901 | — |
Reaction Steps
The imidazo[4,5-c]quinoline system is synthesised starting from 4-chloro-3-nitroquinolines D which are activated in the 6-position by a leaving group EWG, for example halogen, triflate or mesylate. Preferably 4-chloro-6-iodo-3-nitro-quinoline (D.1) or 6-bromo-4-chloro-3-nitro-quinoline (D.2) is used.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08895581B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-55e35d52949d4dabb6649f0dc1b8725d |
| Source note | uspto-grants-2014_11 |