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HRID34029

反应详情

EQUATION

反应方程式

HRID 34029 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1ccco1
HCID6919

2-Furancarboxylic acid

C5H4O3

结构：Nc1cc(F)c2[nH]nc(/C=C/c3cccnc3)c2c1
HCID178507809

未命名化合物

PRODUCTS

生成物

1
结构：O=C(Nc1cc(F)c2c(c1)c(/C=C/c1cccnc1)nn2C(=O)c1ccco1)c1ccco1
HCID59797182

未命名化合物

收率 37.9%

PROCEDURE

实验过程

Following amidation using 217 mg of 7-fluoro-3-[(E)-2-(pyridin-3-yl)-vinyl]-1H-indazol-5-ylamine and 286 mg of 2-furancarboxylic acid in accordance with the method of Example 127, purification by LC-MS was carried out, to afford 143 mg of the title compound as yellow crystals.

WORKUP

后处理

  1. customwith the method of Example 127, purification by LC-MS