HRID340362

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID4555750

未命名化合物

结构：Cc1ccc2c(c1)nc(N)c1ncc(CCc3ccc(O)cc3C)cc12

HCID58166509

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc2c(c1)nc(N)c1ncc(CCc3ccc(OCCOCCO[Si](C)(C)C(C)(C)C)cc3C)cc12

HCID66875193

未命名化合物

PROCEDURE

实验过程

2-(4-(2-(2-(Tert-butyldimethylsilyloxy)ethoxy)ethoxy)-2-methylphenethyl)-8-methylbenzo[f][1,7]naphthyridin-5-amine was prepared following an analogous procedure to the preparation described for Example 145/Step 1, but using 4-(2-(5-amino-8-methylbenzo[f][1,7]naphthyridin-2-yl)ethyl)-3-methylphenol (from Example 50) with tert-butyl(2-(2-chloroethoxy)ethoxy)dimethylsilane.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f2eb2d3eb06d43358278a710dd3e9ca7
来源数据集: uspto-grants-2014_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08895577B2
来源说明: uspto-grants-2014_11

反应 SMILES

[NH2:1][C:2]1[C:11]2[N:10]=[CH:9][C:8]([CH2:12][CH2:13][C:14]3[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][C:15]=3[CH3:21])=[CH:7][C:6]=2[C:5]2[CH:22]=[CH:23][C:24]([CH3:26])=[CH:25][C:4]=2[N:3]=1.[C:27]([Si:31]([O:34][CH2:35][CH2:36][O:37][CH2:38][CH2:39]Cl)([CH3:33])[CH3:32])([CH3:30])([CH3:29])[CH3:28]>>[Si:31]([O:34][CH2:35][CH2:36][O:37][CH2:38][CH2:39][O:20][C:17]1[CH:18]=[CH:19][C:14]([CH2:13][CH2:12][C:8]2[CH:9]=[N:10][C:11]3[C:6]([CH:7]=2)=[C:5]2[CH:22]=[CH:23][C:24]([CH3:26])=[CH:25][C:4]2=[N:3][C:2]=3[NH2:1])=[C:15]([CH3:21])[CH:16]=1)([C:27]([CH3:30])([CH3:29])[CH3:28])([CH3:33])[CH3:32]