HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromopyridine → 6-Fluoro-3-[(E)-2-(pyridin-3-yl)-vinyl]-1-trityl-1H-indazole-5-carboxylic Acid Methyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromopyridine | HCID 12286 | — |
| Reactant | 6-fluoro-1-trityl-3-vinyl-1H-indazole-5-carboxylic acid methyl ester | HCID 68930321 | — |
| Product | 6-Fluoro-3-[(E)-2-(pyridin-3-yl)-vinyl]-1-trityl-1H-indazole-5-carboxylic Acid Methyl Ester | HCID 68930192 | — |
Reaction Steps
600 mg of 6-fluoro-1-trityl-3-vinyl-1H-indazole-5-carboxylic acid methyl ester and 190 μl of 3-bromopyridine were treated in the same manner as described in Example 124, to afford 75 mg of the title compound as a colorless powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07429609B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-726ed31139a1409ea2aa834f4cf22e91 |
| Source note | uspto-grants-2008_09 |