HRID34041

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID12286

3-Bromopyridine

C5H4BrN

结构：C=Cc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(F)c(C(=O)OC)cc12

HCID68930321

未命名化合物

PRODUCTS

生成物

结构：COC(=O)c1cc2c(/C=C/c3cccnc3)nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c2cc1F

HCID68930192

未命名化合物

PROCEDURE

实验过程

600 mg of 6-fluoro-1-trityl-3-vinyl-1H-indazole-5-carboxylic acid methyl ester and 190 μl of 3-bromopyridine were treated in the same manner as described in Example 124, to afford 75 mg of the title compound as a colorless powder.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-726ed31139a1409ea2aa834f4cf22e91
来源数据集: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07429609B2
来源说明: uspto-grants-2008_09

反应 SMILES

[CH3:1][O:2][C:3]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][C:13]=1[F:14])[N:10]([C:15]([C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[N:9]=[C:8]2[CH:34]=[CH2:35])=[O:4].Br[C:37]1[CH:38]=[N:39][CH:40]=[CH:41][CH:42]=1>>[CH3:1][O:2][C:3]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][C:13]=1[F:14])[N:10]([C:15]([C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1)([C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[N:9]=[C:8]2/[CH:34]=[CH:35]/[C:37]1[CH:38]=[N:39][CH:40]=[CH:41][CH:42]=1)=[O:4]