HRID34061

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2734375

2-Naphthaleneboronic acid

C10H9BO2

结构：Ic1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cccnc12

HCID68932363

3-Iodo-1-(triphenylmethyl)-1H-pyrazolo[4,3-b]pyridine

C25H18IN3

PRODUCTS

生成物

结构：c1ccc(C(c2ccccc2)(c2ccccc2)n2nc(-c3ccc4ccccc4c3)c3ncccc32)cc1

HCID68932700

未命名化合物

收率 28.7%

PROCEDURE

实验过程

By treating 731 mg of 3-iodo-1-trityl-1H-pyrazolo[4,3-b]pyridine obtained by Example 418 and 340 mg of 2-naphthalene boronic acid in the manner as described in Production example 194, 210 mg of the title compound was obtained as a colorless powder.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-fe5376172d2748c08c3fccc8b5ac8ca6
来源数据集: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07429609B2
来源说明: uspto-grants-2008_09

反应 SMILES

I[C:2]1[C:6]2=[N:7][CH:8]=[CH:9][CH:10]=[C:5]2[N:4]([C:11]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[N:3]=1.[CH:30]1[C:39]2[C:34](=[CH:35][CH:36]=[CH:37][CH:38]=2)[CH:33]=[CH:32][C:31]=1B(O)O>>[CH:38]1[C:39]2[C:34](=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH:35]=[CH:36][C:37]=1[C:2]1[C:6]2=[N:7][CH:8]=[CH:9][CH:10]=[C:5]2[N:4]([C:11]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[N:3]=1