Trifluoroacetic acid → 3-(3-Fluorophenyl)-1H-pyrazolo[4,3-b]pyridin-5-ylamine

HRID 34070Notes

Reaction equation

HRID 34070 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([C:8]2[C:12]3=[N:13][C:14]([NH2:17])=[CH:15][CH:16]=[C:11]3[N:10](C(C3C=CC=CC=3)(C3C=CC=CC=3)C3C=CC=CC=3)[N:9]=2)[CH:5]=[CH:6][CH:7]=1.FC(F)(F)C(O)=O>>[F:1][C:2]1[CH:3]=[C:4]([C:8]2[C:12]3=[N:13][C:14]([NH2:17])=[CH:15][CH:16]=[C:11]3[NH:10][N:9]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 68927323HCID 68927323, compound

Product 1

HCID 597971963-(3-Fluorophenyl)-1H-pyrazolo[4,3-b]pyridin-5-ylamine

Procedure

3-(3-Fluorophenyl)-1-trityl-1H-pyrazolo[4,3-b]pyridin-5-ylamine was treated with trifluoroacetic acid in the similar method as described in Example 16 and so on, followed by purification by LC-MS, to give the title compound.

Workup

  1. customso on, followed by purification by LC-MS

Sources & evidence

ORD record
ord-4c1558569fe64aec909bb24a4616c8a4
Source dataset
uspto-grants-2008_09
Patent number
US07429609B2

Reaction notes

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